Burbur Pinella is the liquid supplement you need to support natural detoxification and healthy brain functions on a daily basis. 2 oz.Start with 2 drops in a 4oz cup of water and wait one minute before drinking. Start with 2 drops, and titrate up 1-2 drops every week until at 40 drops twice a day. Continue at 40 drops twice a day or as directed by your physician/provider.